Topoisomerase II – DNA’s Natural Detangler
DNA is sophisticated. That means that there’s more opportunity for something to go wrong! If your DNA was all knotted up, then you’d be in trouble, but a little enzyme known as Topoisomerase II steps in. How does it work, and what are the implications? Dr. Joe Deweese earned his P.h.D. in Biochemistry from Vanderbilt University and in 2009, began teaching biochemistry and pharmacology at the Lipscomb University College of Pharmacy. His specialty is in DNA Topoisomerases – a fascinating field of research that will leave you in awe of God’s design.
In Topoisomerase II – DNA’s Natural Detangler you will learn that:
“Without Topoisomerase activity, you have no way to alleviate the topological strains, so there is going to be no way to survive. there is no way to replicate your DNA, no way to transcribe your DNA. you have to have this function very early on.” – Joe Deweese
Also check out The Design and Complexity of DNA Trilogy Video Series
Ann (verified owner) –
Very good. Very thought provoking. When Dr. Deweese briefly described the cancer treatment he made the disclaimer that although the cancer drug may work in preventing cancer cell replication yet it causes adverse effects because the topoisomerase II is affected in healthy cells too. That got me to thinking. Our DNA is so complex, so intertwined functionally that to interfere in one process can mess up another process. In fact, changing one thing has the potential to change everything. We have an amazing God who created all this at the same time so it can work properly, and we as humans need to be careful not to think too highly of ourselves in believing we can do better than God. We can’t. We need to be careful that we don’t mess this incredibly complex system up. We are fearfully and wonderfully made, and DNA is the epitome of that verse.